The progression of research and scholarly inquiry does not occur in isolation and is wholly dependent on accurate reporting of methods and results, and successful replication of prior work. Without mechanisms to correct the literature, much time and money is wasted on research based on a crumbling foundation. These guidelines serve to outline the respective responsibilities of researchers, institutions, agencies, and publishers or editors in maintaining the integrity of the research record. Delineating these complementary roles and proposing solutions for common (...) barriers provide a foundation for best practices. (shrink)

Alice B. Stockham took 'KAREZZA' from the Italian term 'carezza' meaning petting or gentle stroking. Because of birth control as well as 'spiritual exaltation' she pled for a radical change of sexual behavior. She was convinced, that there was a tremendous difference between the usual copulation ending with orgasm respectively ejaculation and the sexual merging according to the Karezza technique without a climax. In spite of the 'sexual revolutions' during the 20th century her Karezza method has been generally ignored (...) until today. But it may give men and women a chance to control the sexual drive by means of their own mental power which can be successfully trained. (shrink)

Titin, the largest protein identified to date (over 1 μm long, almost 3 million daltons in mass) is the third most abundant component of the sarcomere. In the mature myofibril, titin molecules span from M line to Z line, forming a third filament system which provides sarcomeric alignment and elastic recoil. In the developing sarcomere, accumulating evidence from studies both in vivo and in vitro implicates titin as part of a morphogenetic scaffolding, upon which critical events in myofibrillogenesis are coordinated (...) in a time‐ and spacedependent manner. (shrink)

“Structural racism in the COVID-19 pandemic: moving forward” offers a nuanced and important critique of racial and ethnic health disparities starkly illuminated by COVID-19....

Anthropological analysis of religion, following Bronislaw Mahowski, is founded in empirical observational data gained at least in part by participant observation. Malinowski described religion as a “sociological charter” which is a “retrospective moral pattern of behavior,” constructed as a myth after the fact of behavior. Anthony F. C. Wallace's revitalization model provides the mechanism through which the Malinowskian charter is developed. Jack Wilson's Ghost Dance religion is briefly described as an example of a revitalization movement, and it is suggested that (...) both contemporary peace movements and militant Christian movements are revitalization movements. (shrink)

. Gender is a social construct. Technically, it is a grammatical structuring category that may refer to sex, as is typical of Indo‐European languages, or to another set of features such as animate versus inanimate, as is typical of Algonkian languages. Gender in language forces speakers of the language to be continually conscious of application of the category, and they tend to project the categorization into their experience of the world and collocate observations under these broad categories. Western science has (...) been developed by speakers of Indo‐European languages employing male/female genders, and in a cultural tradition that at least since the time of Classical Greece has collocated male with active, creative, rational, and public /dominant , and female with passive, irrational/emotional, and private /subordinate. Religion and science‐organons for rendering existential experience intelligible‐have always been used by the dominant class as instruments of power, and therefore in Western cultures have been entangled with legitimization of a congeries of concepts collocated with male gender. This paper illustrates the social construction of this congeries by contrasting it with non‐Western usages and valuations. (shrink)

A method of developing a relational semantics and relational proof systems for many-valued logics based on finite algebras of truth values is presented. The method is applied to Rosser-Turquette logic, logics based on symmetric Heyting algebras with operators and a Post-style logic.

Previous meta-analyses support a female advantage in decoding non-verbal emotion (Hall, 1978, 1984), yet the mechanisms underlying this advantage are not understood. The present study examined whether the female advantage is related to greater female attention to the eyes. Eye-tracking techniques were used to measure attention to the eyes in 19 males and 20 females during a facial expression recognition task. Women were faster and more accurate in their expression recognition compared with men, and women looked more at the eyes (...) than men. Positive relationships were observed between dwell time and number of fixations to the eyes and both accuracy of facial expression recognition and speed of facial expression recognition. These results support the hypothesis that the female advantage in facial expression recognition is related to greater female attention to the eyes. (shrink)

Chronic post-surgical pain (CPSP) represents a highly prevalent and significant clinical problem. Both major and minor surgeries entail risks of developing CPSP, and cancer-related surgery is no exception. As an example, more than 40% of women undergoing breast cancer surgery struggle with CPSP years after surgery. While we do not fully understand the pathophysiology of CPSP, we know it is multifaceted with biological, social, and psychological factors contributing. The aim of this review is to advocate for the role of response (...) outcome expectancies in the development of CPSP following breast cancer surgery. We propose the Cognitive Activation Theory of Stress (CATS) as an applicable theoretical framework detailing the potential role of cortisol regulation, inflammation, and inflammatory-induced sickness behavior in CPSP. Drawing on learning theory and activation theory, CATS offers psychobiological explanations for the relationship between stress and health, where acquired expectancies are crucial in determining the stress response and health outcomes. Based on existing knowledge about risk factors for CPSP, and in line with the CATS position, we propose the SURGEry outcome expectancy (SURGE) model of CPSP. According to SURGE, expectancies impact stress physiology, inflammation, and fear-based learning influencing the development and persistence of CPSP. SURGE further proposes that generalized response outcome expectancies drive adaptive or maladaptive stress responses in the time around surgery, where coping dampens the stress response, while helplessness and hopelessness sustains it. A sustained stress response may contribute to central sensitization, alterations in functional brain networks and excessive fear-based learning. This sets the stage for a prolonged state of inflammatory-induced sickness behavior – potentially driving and maintaining CPSP. Finally, as psychological factors are modifiable, robust and potent predictors of CPSP, we suggest hypnosis as an effective intervention strategy targeting response outcome expectancies. We here argue that presurgical clinical hypnosis has the potential of preventing CPSP in women with breast cancer. (shrink)

Logically, weighting is transitive, but similarity is not, so clustering cannot be either. Entailments must help a child to review attribute lists more efficiently. Children's understanding of exceptions to generic claims precedes their ability to articulate explanations. So agency, as enabling constraint, may show coherent covariation with attributes, as mere extensional, observable effect of intensional entailments.

Endosex, in contrast to intersex, refers to innate physical sex characteristics judged to fall within the broad range of what is considered normative or typical for ‘binary’ female or male bodies by the medical field, or to persons with such characteristics1 (p. 437). In this short contribution, we explain the origins and increasing use of this little-known term and discuss its practical and ethical relevance to medicine as well as to scholarship from a range of disciplines concerned with individuals’ sexed (...) embodiment. There is growing awareness in many quarters of the term intersex— used within some discourses to refer to clusters of bodily attributes (as in ‘intersex traits’, also termed differences of sex development or variations of sex characteristics)1 or more broadly to persons (as in ‘intersex persons’) whose bodily attributes differ from the dominant clinical, biological, or legal paradigms that categorise and differentiate female and male bodies. Intersex traits have historically been stigmatised as monstrous, morbid or tragic, justifying surgical and hormonal ‘fixing’.2 Persons born with the attributes named with these terms, even if physically healthy, therefore risk unnecessary pathologisation and medicalisation, prompting interventions, often non-voluntary, into their bodies to make them appear or function in ways that are deemed more typically female or male. In addition, some legal and social systems automatically associate persons with these traits with third categories of sex—neither female nor male—which may or may not align with their sex designation at birth, sex of rearing, personal experience or self-conception (see Coda). Being seen as intersex or being judged to have …. (shrink)

"A Handbook of Traditional Living" consists of two texts originally published by the Italian cultural organization Raido, translated here for the first time: "The World of Tradition," a comprehensive summary of the principle ideas of Julius Evola; and "The Front of Tradition," a more practical guide for living as a traditionalist.

The analysis offered by Dixon et al. fails to acknowledge that the attitudes that drive prejudice are attitudes that are constructed in particular contexts. These attitudes can diverge strongly from attitudes toward the group in general. Social change is thus best achieved through challenging the requirements of roles and by changing group stereotypes.

The topic of temporal meaning in texts has received considerable attention in recent years from scholars in linguistics, logical semantics, cognitive science, and artificial intelligence. Representing Time in Natural Language offers a systematic and detailed account of how we use temporal information contained in a text or in discourse to reason about the flow of time, inferring the order in which events happened when this is not explicitly stated. A new representational system is designed to formalize an appropriately context-dependent notion (...) of situated inference. The Dynamic Aspect Tree, representing temporal dependencies, constitutes a novel and important dynamic temporal logic, one that makes it easy to see "what follows when" from the information given in an ordinary English text. (shrink)

Background: Black, Asian and minority ethnic groups have a high need for organ transplantation but deceased donation is low. This restricts the availability of well-matched organs and results in relatively long waiting times for transplantation, with increased mortality risks. Objective: To identify barriers to organ donor registration and family consent among the BAME population, and to develop and evaluate a training intervention to enhance communication with ethnic minority families and identify impacts on family consent. Methods: Three-phase programme comprising community-based research (...) involving two systematic reviews examining attitudes and barriers to organ donation and effective interventions followed by 22 focus groups with minority ethnic groups; hospital-based research examining staff practices and influences on family consent through ethics discussion groups with staff, a study on intensive care units and interviews with bereaved ethnic minority families; and development and evaluation of a training package to enhance cultural competence among ICU staff. Setting: Community focus group study in eight London boroughs with high prevalence of ethnic minority populations. Hospital studies at five NHS hospital trusts. Participants: Community studies: 228 focus group participants; hospital studies: 35 nurses, 28 clinicians, 19 hospital chaplains, 25 members of local Organ Donation Committees, 17 bereaved family members; and evaluation: 66 health professionals. Data sources: Focus groups with community residents, systematic reviews, qualitative interviews and observation in ICUs, EDGs with ICU staff, bereaved family interviews and questionnaires for trial evaluation. Review methods: Systematic review and narrative synthesis. Results: Community studies: Organ Donor Register – different ethnic/faith and age groups were at varying points on the ‘pathway’ to organ donor registration, with large numbers lacking knowledge and remaining at a pre-contemplation stage. Key attitudinal barriers were uncertainties regarding religious permissibility, bodily concerns, lack of trust in health professionals and little priority given to registration, with the varying significance of these factors varying by ethnicity/faith and age. National campaigns focusing on ethnic minorities have had limited impact, whereas characteristics of effective educational interventions are being conducted in a familiar environment; addressing the groups’ particular concerns; delivery by trained members of the lay community; and providing immediate access to registration. Interventions are also required to target those at specific stages of the donation pathway. Hospital studies: family consent to donation – many ICU staff, especially junior nurses, described a lack of confidence in communication and supporting ethnic minority families, often reflecting differences in emotional expression, faith and cultural beliefs, and language difficulties. The continuing high proportion of family donation discussions that take place without the collaboration of a specialist nurse for organ donation reflected consultants’ views of their own role in family consent to donation, a lack of trust in SNODs and uncertainties surrounding controlled donations after circulatory death. Hospital chaplains differed in their involvement in ICUs, reflecting their availability/employment status, personal interests and the practices of ICU staff. Evaluation: professional development package – a digital versatile disk-based training package was developed to promote confidence and skills in cross-cultural communication. Initial evaluation produced positive feedback and significant affirmative attitudinal change but no significant difference in consent rate over the short follow-up period with requirements for longer-term evaluation. Limitations: Participants in the focus group study were mainly first-generation migrants of manual socioeconomic groups. It was not permitted to identify non-consenting families for interview with data regarding the consent process were therefore limited to consenting families. Conclusions: The research presents guidance for the effective targeting of donation campaigns focusing on minority ethnic groups and provides the first training package in cultural competence in the NHS. Future work: Greater evaluation is required of community interventions in the UK to enhance knowledge of effective practice and analysis of the experiences of non-consenting ethnic minority families. Funding: The National Institute for Health Research Programme Grants for Applied Research programme. (shrink)

Modelling human reasoning characterizes the fundamental human cognitive capacity to describe our past experience and use it to form expectations as well as plan and direct our future actions. Natural language semantics analyzes dynamic forms of reasoning in which the real-time order determines the temporal relations between the described events, when reported with telic simple past-tense clauses. It provides models of human reasoning that could supplement ACT-R models.